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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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DBCO-PEG3-acid is a dibenzocyclooctyne (DBCO)-containing PEG linker designed for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition) in bioconjugation and antibody-drug conjugate synthesis. It is a non-cleavable linker supplied as a solid for laboratory use.
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Elastin methacrylated is a methacrylated elastin polymer designed as a photocrosslinkable hydrogel precursor for 3D bioprinting, cell culture, and tissue engineering. It promotes immune cell recruitment and supports angiogenesis and collagen deposition when formed into hydrogels and cured under blue light.
Photocrosslinkable hydrogel precursor suitable for 3D bioprinting and cell culture.
Promotes recruitment of innate immune cells and supports angiogenesis and tissue regeneration.
Forms fibrous hydrogels with tunable mechanical properties at higher concentrations.
Compatible with blue-light photoinitiators and curing at 365-405 nm.
Can be sterilized by 0.22 μm filtration; avoid repeated freeze-thaw cycles.
Stable as a powder at -20°C; store solutions cold and minimize room temperature exposure.
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Azido-PEG3-propionic acid tert-butyl ester is an azide-functionalized, Boc-protected PEG3 linker for bioconjugation. It acts as a cleavable three-unit PEG spacer and an azide reagent for click chemistry, suitable for assembling antibody-drug conjugates and PROTACs.
Azide-functionalized Boc-protected PEG3 linker.
Cleavable three-unit PEG spacer for ADC and PROTAC synthesis.
Suitable for CuAAC and SPAAC click chemistry.
Purity ≥98.0%.
Molecular weight 303.35 g/mol; formula C13H25N3O5.
Appearance colorless to light yellow liquid; follow storage recommendations.
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THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound is intended for research use only and is not sold to patients.
Enables the synthesis of PROTACs
Functions as a PROTAC linker
Utilizes the PROTAC pathway
Facilitates selective degradation of target proteins via the ubiquitin-proteasome system
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N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
PEG-based PROTAC linker.
Used in the synthesis of PROTACs.
Click chemistry reagent.
Contains an azide group.
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups.
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
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2',3'-O-isopropylidene-6-mercaptopurine riboside is an isopropylidene-protected nucleoside derivative used as a research reagent with notable metal complexing activity. It is supplied as a solid for laboratory use and should be handled and stored under appropriate conditions to preserve stability.
CAS number 5856-48-4.
Molecular formula C13H16N4O4S.
Molecular weight 324.36.
Purity approximately 96.6%.
Packaged quantity 50 MG.
Appearance solid, white to off-white.
Storage: powder at -20°C up to 3 years; in solvent -80°C for 6 months or -20°C for 1 month.
Application for studying metal complexing mechanisms in research.
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(S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid (Boc-his(trt)-aib-ohol) is a drug intermediate for synthesis of various active compounds
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It is utilized in the synthesis of PROTAC SGK3 degrader-1, a potent SGK3 degrader based on PROTAC technology. This product is for research use only.
Molecular weight: 296.40
Formula: C17H28O4
Appearance: Liquid (density: 1.031 g/cm³)
Color: Colorless to light yellow
Shipping: Room temperature in continental US
Pure form storage: -20°C for 3 years, 4°C for 2 years
In solvent storage: -80°C for 6 months, -20°C for 1 month
In vitro solubility: ≥ 100 mg/mL in DMSO
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Sitafloxacin hydrate is an orally active fluoroquinolone antibiotic with in vitro activity against a broad spectrum of Gram-positive and -negative bacteria, including anaerobic bacteria and atypical pathogens. It is utilized in the study of respiratory and urinary tract infections, and exhibits good activity against Mycobacterium avium in vivo.
Orally active fluoroquinolone antibiotic
Active against a broad spectrum of Gram-positive and -negative bacteria
Effective against anaerobic bacteria and atypical pathogens
Used in respiratory tract infection studies
Used in urinary tract infection studies
Shows good activity against Mycobacterium avium in mice
Eliminates bacteria in the spleen and lungs
Demonstrates strong activity against mycobacteria in macrophages
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Bis-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Intended for research use only
Not sold to patients
Viscous liquid appearance
Colorless to light yellow color
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